TY  - GEN
AU  - Hinze,Laura
AU  - Pfirrmann,Maren
AU  - Karim,Salmaan
AU  - Degar,James
AU  - McGuckin,Connor
AU  - Vinjamur,Divya
AU  - Sacher,Joshua
AU  - Stevenson,Kristen E
AU  - Neuberg,Donna S
AU  - Orellana,Esteban
AU  - Stanulla,Martin
AU  - Gregory,Richard I
AU  - Bauer,Daniel E
AU  - Wagner,Florence F
AU  - Stegmaier,Kimberly
AU  - Gutierrez,Alejandro
TI  - Synthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias
SN  - 1878-3686
PY  - 2020///0203
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Asparaginase
KW  - Cell Death
KW  - drug effects
KW  - Dose-Response Relationship, Drug
KW  - Drug Resistance, Neoplasm
KW  - Glycogen Synthase Kinase 3 beta
KW  - antagonists & inhibitors
KW  - Humans
KW  - Jurkat Cells
KW  - Leukemia
KW  - drug therapy
KW  - Male
KW  - Mice, Inbred NOD
KW  - Mice, Transgenic
KW  - Polyethylene Glycols
KW  - Proteasome Endopeptidase Complex
KW  - metabolism
KW  - Protein Kinase Inhibitors
KW  - Protein Stability
KW  - Proteolysis
KW  - Synthetic Lethal Mutations
KW  - THP-1 Cells
KW  - Ubiquitination
KW  - Wnt Signaling Pathway
KW  - genetics
KW  - Wnt3A Protein
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.ccell.2019.03.004
ER  -