Hinze, Laura <br/><br/>
Synthetic Lethality of Wnt Pathway Activation and Asparaginase in Drug-Resistant Acute Leukemias.  [electronic resource] 

 -  Cancer cell  04 2019 
 - 664-676.e7 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1878-3686 
<br/><br/><label>Standard No.: </label>10.1016/j.ccell.2019.03.004  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--pharmacology<br/>Asparaginase--pharmacology<br/>Cell Death--drug effects<br/>Dose-Response Relationship, Drug<br/>Drug Resistance, Neoplasm<br/>Glycogen Synthase Kinase 3 beta--antagonists & inhibitors<br/>Humans<br/>Jurkat Cells<br/>Leukemia--drug therapy<br/>Male<br/>Mice, Inbred NOD<br/>Mice, Transgenic<br/>Polyethylene Glycols--pharmacology<br/>Proteasome Endopeptidase Complex--metabolism<br/>Protein Kinase Inhibitors--pharmacology<br/>Protein Stability<br/>Proteolysis<br/>Synthetic Lethal Mutations<br/>THP-1 Cells<br/>Ubiquitination<br/>Wnt Signaling Pathway--genetics<br/>Wnt3A Protein--genetics<br/>Xenograft Model Antitumor Assays