TY - GEN AU - Kvarnhammar,Anne Månsson AU - Veitonmäki,Niina AU - Hägerbrand,Karin AU - Dahlman,Anna AU - Smith,Karin Enell AU - Fritzell,Sara AU - von Schantz,Laura AU - Thagesson,Mia AU - Werchau,Doreen AU - Smedenfors,Kristine AU - Johansson,Maria AU - Rosén,Anna AU - Åberg,Ida AU - Winnerstam,Magnus AU - Nyblom,Eva AU - Barchan,Karin AU - Furebring,Christina AU - Norlén,Per AU - Ellmark,Peter TI - The CTLA-4 x OX40 bispecific antibody ATOR-1015 induces anti-tumor effects through tumor-directed immune activation SN - 2051-1426 PY - 2020///0707 KW - Animals KW - Antibodies, Bispecific KW - pharmacology KW - CHO Cells KW - CTLA-4 Antigen KW - antagonists & inhibitors KW - Cell Line, Tumor KW - transplantation KW - Cricetulus KW - Disease Models, Animal KW - Drug Screening Assays, Antitumor KW - Female KW - HEK293 Cells KW - Humans KW - Male KW - Mice KW - Mice, Transgenic KW - Primary Cell Culture KW - Proof of Concept Study KW - Receptors, OX40 KW - agonists KW - T-Lymphocytes, Regulatory KW - drug effects KW - Urinary Bladder Neoplasms KW - drug therapy N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1186/s40425-019-0570-8 ER -