Inhibition of HMGB1/RAGE-mediated endocytosis by HMGB1 antagonist box A, anti-HMGB1 antibodies, and cholinergic agonists suppresses inflammation. [electronic resource]
- Molecular medicine (Cambridge, Mass.) 04 2019
- 13 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural
1528-3658
10.1186/s10020-019-0081-6 doi
Acetylcholine--pharmacology Animals Cells, Cultured Cholinergic Agonists--pharmacology Endocytosis--drug effects Enzyme-Linked Immunosorbent Assay HMGB1 Protein--metabolism Inflammation--metabolism Lipopolysaccharides--pharmacology Macrophages--drug effects Mice Mice, Inbred BALB C Microscopy, Fluorescence RAW 264.7 Cells Receptor for Advanced Glycation End Products--metabolism