Ng-Blichfeldt, John-Poul

TGF-β activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation. [electronic resource] - American journal of physiology. Lung cellular and molecular physiology 07 2019 - L14-L28 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1522-1504

10.1152/ajplung.00400.2018 doi


Adult Stem Cells--drug effects
Aged
Animals
Cell Communication--drug effects
Cell Differentiation--drug effects
Coculture Techniques
Epithelial Cell Adhesion Molecule--genetics
Epithelial Cells--drug effects
Female
Fibroblast Growth Factor 7--pharmacology
Fibroblasts--metabolism
Gene Expression Profiling
Gene Expression Regulation
Hepatocyte Growth Factor--pharmacology
Humans
Lung--metabolism
Male
Mice
Mice, Inbred C57BL
Middle Aged
Myofibroblasts--drug effects
Organoids--drug effects
Pulmonary Disease, Chronic Obstructive--genetics
Pyridines--pharmacology
Pyrimidines--pharmacology
Transforming Growth Factor beta--metabolism
Wnt Proteins--genetics
Wnt Signaling Pathway
beta Catenin--genetics