TY - GEN AU - Hounjet,Judith AU - Habets,Roger AU - Schaaf,Marco B AU - Hendrickx,Tessa C AU - Barbeau,Lydie M O AU - Yahyanejad,Sanaz AU - Rouschop,Kasper M AU - Groot,Arjan J AU - Vooijs,Marc TI - The anti-malarial drug chloroquine sensitizes oncogenic NOTCH1 driven human T-ALL to γ-secretase inhibition SN - 1476-5594 PY - 2020///0214 KW - Amyloid Precursor Protein Secretases KW - antagonists & inhibitors KW - Antimalarials KW - pharmacology KW - Apoptosis KW - drug effects KW - Cell Cycle KW - Cell Line, Tumor KW - Cell Proliferation KW - Chloroquine KW - DNA Damage KW - Enzyme Inhibitors KW - Humans KW - Ligands KW - Precursor T-Cell Lymphoblastic Leukemia-Lymphoma KW - metabolism KW - Reactive Oxygen Species KW - Receptor, Notch1 KW - Signal Transduction N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/s41388-019-0802-x ER -