Hounjet, Judith <br/><br/>
The anti-malarial drug chloroquine sensitizes oncogenic NOTCH1 driven human T-ALL to γ-secretase inhibition.  [electronic resource] 

 -  Oncogene  07 2019 
 - 5457-5468 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1476-5594 
<br/><br/><label>Standard No.: </label>10.1038/s41388-019-0802-x  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amyloid Precursor Protein Secretases--antagonists & inhibitors<br/>Antimalarials--pharmacology<br/>Apoptosis--drug effects<br/>Cell Cycle--drug effects<br/>Cell Line, Tumor<br/>Cell Proliferation--drug effects<br/>Chloroquine--pharmacology<br/>DNA Damage<br/>Enzyme Inhibitors--pharmacology<br/>Humans<br/>Ligands<br/>Precursor T-Cell Lymphoblastic Leukemia-Lymphoma--metabolism<br/>Reactive Oxygen Species--metabolism<br/>Receptor, Notch1--metabolism<br/>Signal Transduction--drug effects