TY - GEN AU - Yang,Sumin AU - Lee,Wonhwa AU - Lee,Bong-Seon AU - Lee,Changhun AU - Park,Eui Kyun AU - Ku,Sae-Kwang AU - Bae,Jong-Sup TI - Aloin Reduces HMGB1-Mediated Septic Responses and Improves Survival in Septic Mice by Activation of the SIRT1 and PI3K/Nrf2/HO-1 Signaling Axis SN - 1793-6853 PY - 2019///1017 KW - Aloe KW - chemistry KW - Animals KW - Disease Models, Animal KW - Emodin KW - administration & dosage KW - HMGB1 Protein KW - antagonists & inhibitors KW - Heme Oxygenase-1 KW - metabolism KW - Human Umbilical Vein Endothelial Cells KW - Humans KW - Male KW - Mice, Inbred C57BL KW - NF-E2-Related Factor 2 KW - Phosphatidylinositol 3-Kinases KW - Phytotherapy KW - Sepsis KW - drug therapy KW - Signal Transduction KW - drug effects KW - Sirtuin 1 N1 - Publication Type: Journal Article UR - https://doi.org/10.1142/S0192415X19500320 ER -