TY - GEN AU - Ng,Kimmie AU - Nimeiri,Halla S AU - McCleary,Nadine J AU - Abrams,Thomas A AU - Yurgelun,Matthew B AU - Cleary,James M AU - Rubinson,Douglas A AU - Schrag,Deborah AU - Miksad,Rebecca AU - Bullock,Andrea J AU - Allen,Jill AU - Zuckerman,Dan AU - Chan,Emily AU - Chan,Jennifer A AU - Wolpin,Brian M AU - Constantine,Michael AU - Weckstein,Douglas J AU - Faggen,Meredith A AU - Thomas,Christian A AU - Kournioti,Chryssanthi AU - Yuan,Chen AU - Ganser,Christine AU - Wilkinson,Brittney AU - Mackintosh,Christopher AU - Zheng,Hui AU - Hollis,Bruce W AU - Meyerhardt,Jeffrey A AU - Fuchs,Charles S TI - Effect of High-Dose vs Standard-Dose Vitamin D3 Supplementation on Progression-Free Survival Among Patients With Advanced or Metastatic Colorectal Cancer: The SUNSHINE Randomized Clinical Trial SN - 1538-3598 PY - 2019///0422 KW - Adenocarcinoma KW - drug therapy KW - Aged KW - Antineoplastic Combined Chemotherapy Protocols KW - therapeutic use KW - Cholecalciferol KW - administration & dosage KW - Colorectal Neoplasms KW - Dietary Supplements KW - Dose-Response Relationship, Drug KW - Double-Blind Method KW - Female KW - Humans KW - Male KW - Middle Aged KW - Multivariate Analysis KW - Neoplasm Staging KW - Progression-Free Survival KW - Proportional Hazards Models KW - Vitamin D KW - analogs & derivatives KW - Vitamins N1 - Publication Type: Clinical Trial, Phase II; Comparative Study; Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, N.I.H., Extramural UR - https://doi.org/10.1001/jama.2019.2402 ER -