Dong, Qiuju

PCC0208027, a novel tyrosine kinase inhibitor, inhibits tumor growth of NSCLC by targeting EGFR and HER2 aberrations. [electronic resource] - Scientific reports 04 2019 - 5692 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2045-2322

10.1038/s41598-019-42245-3 doi


Animals
Antineoplastic Agents--pharmacology
Carcinoma, Non-Small-Cell Lung--drug therapy
Cell Line, Tumor
ErbB Receptors--genetics
Female
Gene Expression Regulation, Neoplastic
Humans
Lung Neoplasms--drug therapy
Mice
Mice, Inbred BALB C
Mice, Nude
Mutation
Piperazines--pharmacology
Protein Kinase Inhibitors--pharmacology
Receptor, ErbB-2--genetics
Receptor, ErbB-4--genetics
Signal Transduction
Xenograft Model Antitumor Assays