Alternative splicing of the tumor suppressor ASPP2 results in a stress-inducible, oncogenic isoform prevalent in acute leukemia. [electronic resource]
- EBioMedicine Apr 2019
- 340-351 p. digital
Publication Type: Journal Article
2352-3964
10.1016/j.ebiom.2019.03.028 doi
Alternative Splicing Apoptosis Regulatory Proteins--genetics Cell Line, Tumor Cytogenetics Gene Expression Regulation, Neoplastic Genes, Tumor Suppressor Humans Leukemia, Myeloid, Acute--genetics Neoplastic Stem Cells--metabolism Precursor Cell Lymphoblastic Leukemia-Lymphoma--genetics Protein Biosynthesis Protein Isoforms--genetics Stress, Physiological--genetics Tumor Suppressor Protein p53--genetics