TY  - GEN
AU  - Prabhu,Kirti S
AU  - Siveen,Kodappully S
AU  - Kuttikrishnan,Shilpa
AU  - Jochebeth,Anh
AU  - Ali,Tayyiba A
AU  - Elareer,Noor R
AU  - Iskandarani,Ahmad
AU  - Quaiyoom Khan,Abdul
AU  - Merhi,Maysaloun
AU  - Dermime,Said
AU  - El-Elimat,Tamam
AU  - Oberlies,Nicholas H
AU  - Alali,Feras Q
AU  - Steinhoff,Martin
AU  - Uddin,Shahab
TI  - Greensporone A, a Fungal Secondary Metabolite Suppressed Constitutively Activated AKT via ROS Generation and Induced Apoptosis in Leukemic Cell Lines
SN  - 2218-273X
PY  - 2019///0903
KW  - Antineoplastic Agents
KW  - chemistry
KW  - Apoptosis
KW  - drug effects
KW  - Ascomycota
KW  - Cell Proliferation
KW  - Dose-Response Relationship, Drug
KW  - Drug Screening Assays, Antitumor
KW  - Humans
KW  - Macrolides
KW  - Membrane Potential, Mitochondrial
KW  - Molecular Structure
KW  - Proto-Oncogene Proteins c-akt
KW  - Reactive Oxygen Species
KW  - analysis
KW  - Secondary Metabolism
KW  - Structure-Activity Relationship
KW  - Tumor Cells, Cultured
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.3390/biom9040126
ER  -