TY - GEN AU - Beuckmann,Carsten Theodor AU - Ueno,Takashi AU - Nakagawa,Makoto AU - Suzuki,Michiyuki AU - Akasofu,Shigeru TI - Preclinical in vivo characterization of lemborexant (E2006), a novel dual orexin receptor antagonist for sleep/wake regulation SN - 1550-9109 PY - 2020///0420 KW - Acetamides KW - pharmacology KW - Adrenocorticotropic Hormone KW - blood KW - Animals KW - Female KW - Hypnotics and Sedatives KW - Isoquinolines KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Orexin Receptor Antagonists KW - Orexin Receptors KW - metabolism KW - Pyridines KW - Pyrimidines KW - Rats KW - Rats, Sprague-Dawley KW - Sleep Initiation and Maintenance Disorders KW - drug therapy KW - Sleep, REM KW - drug effects KW - Wakefulness KW - physiology KW - Zolpidem N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1093/sleep/zsz076 ER -