TY - GEN AU - Deng,Xufang AU - Mettelman,Robert C AU - O'Brien,Amornrat AU - Thompson,John A AU - O'Brien,Timothy E AU - Baker,Susan C TI - Analysis of Coronavirus Temperature-Sensitive Mutants Reveals an Interplay between the Macrodomain and Papain-Like Protease Impacting Replication and Pathogenesis SN - 1098-5514 PY - 2020///0623 KW - Animals KW - Cell Line KW - Coronavirus KW - metabolism KW - Coronavirus Infections KW - Coronavirus Papain-Like Proteases KW - HEK293 Cells KW - Humans KW - Immunity, Innate KW - immunology KW - Interferon Type I KW - Mice KW - Murine hepatitis virus KW - genetics KW - Papain KW - Peptide Hydrolases KW - Protein Domains KW - Temperature KW - Viral Nonstructural Proteins KW - Virulence Factors KW - Virus Replication N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1128/JVI.02140-18 ER -