TY - GEN AU - Cockburn,Chelsea L AU - Green,Ryan S AU - Damle,Sheela R AU - Martin,Rebecca K AU - Ghahrai,Naomi N AU - Colonne,Punsiri M AU - Fullerton,Marissa S AU - Conrad,Daniel H AU - Chalfant,Charles E AU - Voth,Daniel E AU - Rucks,Elizabeth A AU - Gilk,Stacey D AU - Carlyon,Jason A TI - Functional inhibition of acid sphingomyelinase disrupts infection by intracellular bacterial pathogens SN - 2575-1077 PY - 2020///0226 KW - Animals KW - Cholesterol, LDL KW - metabolism KW - Desipramine KW - pharmacology KW - Disease Models, Animal KW - Endothelial Cells KW - microbiology KW - Enzyme Inhibitors KW - Gram-Negative Bacteria KW - pathogenicity KW - Gram-Negative Bacterial Infections KW - HeLa Cells KW - Healthy Volunteers KW - Host-Pathogen Interactions KW - drug effects KW - Humans KW - Macaca mulatta KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Mice, Knockout KW - Neutrophils KW - Signal Transduction KW - Sphingomyelin Phosphodiesterase KW - antagonists & inhibitors KW - THP-1 Cells KW - Vacuoles N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.26508/lsa.201800292 ER -