Prototyping kinase inhibitor-cytotoxin anticancer mutual prodrugs activated by tumour hypoxia: A chemical proof of concept study. [electronic resource]
- Bioorganic & medicinal chemistry letters 05 2019
- 1215-1219 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1464-3405
10.1016/j.bmcl.2019.03.015 doi
Alcohols--chemistry Amines--chemistry Antineoplastic Agents--chemical synthesis Cell Line, Tumor Cell Proliferation Cytotoxins--chemistry Drug Screening Assays, Antitumor--methods Floxuridine--chemistry Humans Indoles--chemistry Molecular Structure Prodrugs--chemical synthesis Proof of Concept Study Protein Kinase Inhibitors--chemical synthesis Pyrroles--chemistry Structure-Activity Relationship Tumor Hypoxia