TY - GEN AU - Katona,Bryson W AU - Glynn,Rebecca A AU - Paulosky,Kayla E AU - Feng,Zijie AU - Davis,Caroline I AU - Ma,Jian AU - Berry,Corbett T AU - Szigety,Katherine M AU - Matkar,Smita AU - Liu,Yuanyuan AU - Wang,Haoren AU - Wu,Yuan AU - He,Xin AU - Freedman,Bruce D AU - Brady,Donita C AU - Hua,Xianxin TI - Combined Menin and EGFR Inhibitors Synergize to Suppress Colorectal Cancer via EGFR-Independent and Calcium-Mediated Repression of SKP2 Transcription SN - 1538-7445 PY - 2020///0207 KW - Animals KW - Apoptosis KW - Biomarkers, Tumor KW - genetics KW - Calcium KW - metabolism KW - Cell Proliferation KW - Colorectal Neoplasms KW - drug therapy KW - Drug Synergism KW - Drug Therapy, Combination KW - Enzyme Inhibitors KW - pharmacology KW - ErbB Receptors KW - antagonists & inhibitors KW - Female KW - Gefitinib KW - Gene Expression Regulation, Neoplastic KW - drug effects KW - Humans KW - Inositol 1,4,5-Trisphosphate Receptors KW - Mice KW - Mice, Nude KW - Protein Kinase Inhibitors KW - Proto-Oncogene Proteins KW - S-Phase Kinase-Associated Proteins KW - Thapsigargin KW - Tumor Cells, Cultured KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/0008-5472.CAN-18-2133 ER -