TY - GEN AU - Lynch,Matthew R AU - Tran,Mei T AU - Ralto,Kenneth M AU - Zsengeller,Zsuzsanna K AU - Raman,Vinod AU - Bhasin,Swati S AU - Sun,Nuo AU - Chen,Xiuying AU - Brown,Daniel AU - Rovira,Ilsa I AU - Taguchi,Kensei AU - Brooks,Craig R AU - Stillman,Isaac E AU - Bhasin,Manoj K AU - Finkel,Toren AU - Parikh,Samir M TI - TFEB-driven lysosomal biogenesis is pivotal for PGC1α-dependent renal stress resistance SN - 2379-3708 PY - 2020///0916 KW - Acute Kidney Injury KW - chemically induced KW - Animals KW - Autophagy KW - drug effects KW - Basic Helix-Loop-Helix Leucine Zipper Transcription Factors KW - metabolism KW - CRISPR-Cas Systems KW - Cisplatin KW - toxicity KW - Gene Transfer Techniques KW - Kidney Tubules KW - cytology KW - Lysosomes KW - Mice KW - Mice, Knockout KW - Mice, Transgenic KW - Mitochondria KW - Mitophagy KW - genetics KW - NAD KW - Organelle Biogenesis KW - Oxidative Stress KW - Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha KW - Sequence Analysis, RNA N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1172/jci.insight.126749 ER -