Weaver, James L

BLT-Immune Humanized Mice as a Model for Nivolumab-Induced Immune-Mediated Adverse Events: Comparison of the NOG and NOG-EXL Strains. [electronic resource] - Toxicological sciences : an official journal of the Society of Toxicology 05 2019 - 194-208 p. digital

Publication Type: Comparative Study; Journal Article; Research Support, U.S. Gov't, P.H.S.

1096-0929

10.1093/toxsci/kfz045 doi


Animals
Antineoplastic Agents, Immunological--toxicity
Bone Marrow Transplantation
Female
Genotype
Humans
Immune System--drug effects
Liver Transplantation
Lymphocyte Activation--drug effects
Mice, Inbred NOD
Mice, Transgenic
Nivolumab--toxicity
Programmed Cell Death 1 Receptor--antagonists & inhibitors
Signal Transduction
Species Specificity
T-Lymphocytes--drug effects
Thymus Gland--immunology