Yoon, Hee-Kyung <br/><br/>
The TLR7 agonist imiquimod selectively inhibits IL-4-induced IgE production by suppressing IgG1/IgE class switching and germline ε transcription through the induction of BCL6 expression in B cells.  [electronic resource] 

 -  Cellular immunology  04 2019 
 - 1-8 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1090-2163 
<br/><br/><label>Standard No.: </label>10.1016/j.cellimm.2019.02.006  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antibody Formation<br/>B-Lymphocytes--physiology<br/>CD40 Antigens--metabolism<br/>Cells, Cultured<br/>Gene Expression Regulation<br/>Imiquimod--pharmacology<br/>Immunoglobulin Class Switching<br/>Immunoglobulin E--genetics<br/>Immunoglobulin G--genetics<br/>Immunoglobulin epsilon-Chains--genetics<br/>Interleukin-4--metabolism<br/>Mice<br/>Mice, Inbred C57BL<br/>Proto-Oncogene Proteins c-bcl-6--genetics<br/>RNA, Small Interfering--genetics<br/>Toll-Like Receptor 7--agonists