TY - GEN AU - Hayes,Tikvah K AU - Luo,Flora AU - Cohen,Ofir AU - Goodale,Amy B AU - Lee,Yenarae AU - Pantel,Sasha AU - Bagul,Mukta AU - Piccioni,Federica AU - Root,David E AU - Garraway,Levi A AU - Meyerson,Matthew AU - Johannessen,Cory M TI - A Functional Landscape of Resistance to MEK1/2 and CDK4/6 Inhibition in NRAS-Mutant Melanoma SN - 1538-7445 PY - 2020///0207 KW - Antineoplastic Agents KW - pharmacology KW - Apoptosis KW - Cell Cycle Checkpoints KW - Cell Proliferation KW - Cyclin-Dependent Kinase 4 KW - antagonists & inhibitors KW - Cyclin-Dependent Kinase 6 KW - Drug Resistance, Neoplasm KW - genetics KW - GTP Phosphohydrolases KW - Humans KW - MAP Kinase Kinase 1 KW - MAP Kinase Kinase 2 KW - Melanoma KW - drug therapy KW - Membrane Proteins KW - Mutation KW - Phosphorylation KW - Signal Transduction KW - drug effects KW - Tumor Cells, Cultured N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/0008-5472.CAN-18-2711 ER -