Synthesis of novel chalcones through palladium-catalyzed CO cross-coupling reaction of bromo-chalcones with ethyl acetohydroxamate and their antiplasmodial evaluation against Plasmodium falcipuram in vitro. [electronic resource] - Bioorganic chemistry 05 2019 - 631-640 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1090-2120

10.1016/j.bioorg.2019.02.016 doi


Antimalarials--chemical synthesis
Antineoplastic Agents--chemical synthesis
Carbon--chemistry
Catalysis
Cell Proliferation--drug effects
Cell Survival--drug effects
Chalcones--chemical synthesis
Dose-Response Relationship, Drug
Drug Screening Assays, Antitumor
Hep G2 Cells
Humans
Hydroxamic Acids--chemistry
Molecular Structure
Oxygen--chemistry
Palladium--chemistry
Parasitic Sensitivity Tests
Plasmodium falciparum--drug effects
Structure-Activity Relationship