Double deletion of PINK1 and Parkin impairs hepatic mitophagy and exacerbates acetaminophen-induced liver injury in mice. [electronic resource]
- Redox biology 04 2019
- 101148 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
2213-2317
10.1016/j.redox.2019.101148 doi
Animals Biomarkers Chemical and Drug Induced Liver Injury--etiology Disease Models, Animal Gene Deletion Glutathione--metabolism Hepatocytes--metabolism JNK Mitogen-Activated Protein Kinases--metabolism Male Mice Mice, Knockout Mitochondria, Liver--genetics Mitophagy--genetics Models, Biological Protein Kinases--genetics Ubiquitin-Protein Ligases--genetics