TY - GEN AU - Yu,Yong AU - Qi,Jingjing AU - Xiong,Jieyi AU - Jiang,Liping AU - Cui,Di AU - He,Junlin AU - Chen,Ping AU - Li,Lianjie AU - Wu,Chenjie AU - Ma,Tonghui AU - Shao,Su AU - Wang,Jianjun AU - Yu,Dansong AU - Zhou,Bing AU - Huang,Dongsheng AU - Schmitt,Clemens A AU - Tao,Ran TI - Epigenetic Co-Deregulation of EZH2/TET1 is a Senescence-Countering, Actionable Vulnerability in Triple-Negative Breast Cancer SN - 1838-7640 PY - 2020///0114 KW - Animals KW - Antibiotics, Antineoplastic KW - administration & dosage KW - Apoptosis KW - drug effects KW - Cancer Survivors KW - Cell Line, Tumor KW - Cellular Senescence KW - DNA Methylation KW - DNA, Neoplasm KW - metabolism KW - Doxorubicin KW - Drug Delivery Systems KW - Enhancer of Zeste Homolog 2 Protein KW - antagonists & inhibitors KW - Epigenesis, Genetic KW - Female KW - Gene Expression Regulation, Neoplastic KW - Humans KW - Indazoles KW - pharmacology KW - Mice KW - Mice, Nude KW - Mixed Function Oxygenases KW - Proto-Oncogene Proteins KW - Pyridones KW - Triple Negative Breast Neoplasms KW - genetics KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.7150/thno.29520 ER -