TY  - GEN
AU  - Tinworth,Christopher P
AU  - Lithgow,Hannah
AU  - Dittus,Lars
AU  - Bassi,Zuni I
AU  - Hughes,Sophie E
AU  - Muelbaier,Marcel
AU  - Dai,Han
AU  - Smith,Ian E D
AU  - Kerr,William J
AU  - Burley,Glenn A
AU  - Bantscheff,Marcus
AU  - Harling,John D
TI  - PROTAC-Mediated Degradation of Bruton's Tyrosine Kinase Is Inhibited by Covalent Binding
SN  - 1554-8937
PY  - 2019///1218
KW  - Adenine
KW  - analogs & derivatives
KW  - Agammaglobulinaemia Tyrosine Kinase
KW  - metabolism
KW  - Inhibitor of Apoptosis Proteins
KW  - Piperidines
KW  - Protein Binding
KW  - Protein Kinase Inhibitors
KW  - chemistry
KW  - Proteolysis
KW  - Pyrazoles
KW  - Pyrimidines
KW  - Ubiquitin-Protein Ligases
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1021/acschembio.8b01094
ER  -