TY - GEN AU - Adam,Aziza A A AU - van der Mark,Vincent A AU - Ruiter,Jos P N AU - Wanders,Ronald J A AU - Oude Elferink,Ronald P J AU - Chamuleau,Robert A F M AU - Hoekstra,Ruurdtje TI - Overexpression of carbamoyl-phosphate synthase 1 significantly improves ureagenesis of human liver HepaRG cells only when cultured under shaking conditions SN - 1872-8278 PY - 2020///0427 KW - Ammonia KW - metabolism KW - Arginase KW - biosynthesis KW - Arginine KW - genetics KW - Carbamoyl-Phosphate Synthase (Ammonia) KW - Cell Culture Techniques KW - Cell Line KW - Gene Expression Regulation, Enzymologic KW - Humans KW - Mitochondria, Liver KW - enzymology KW - Ornithine Carbamoyltransferase KW - Up-Regulation KW - Urea N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.mito.2019.02.005 ER -