TY - GEN AU - Serrano,César AU - Mariño-Enríquez,Adrián AU - Tao,Derrick L AU - Ketzer,Julia AU - Eilers,Grant AU - Zhu,Meijun AU - Yu,Channing AU - Mannan,Aristotle M AU - Rubin,Brian P AU - Demetri,George D AU - Raut,Chandrajit P AU - Presnell,Ajia AU - McKinley,Arin AU - Heinrich,Michael C AU - Czaplinski,Jeffrey T AU - Sicinska,Ewa AU - Bauer,Sebastian AU - George,Suzanne AU - Fletcher,Jonathan A TI - Complementary activity of tyrosine kinase inhibitors against secondary kit mutations in imatinib-resistant gastrointestinal stromal tumours SN - 1532-1827 PY - 2019///1216 KW - Animals KW - CHO Cells KW - Clinical Trials, Phase II as Topic KW - Cricetulus KW - Drug Resistance, Neoplasm KW - Female KW - Gastrointestinal Neoplasms KW - drug therapy KW - Gastrointestinal Stromal Tumors KW - Humans KW - Imatinib Mesylate KW - pharmacology KW - Mice KW - Mice, Nude KW - Mutation KW - Phenylurea Compounds KW - Protein Kinase Inhibitors KW - Proto-Oncogene Proteins c-kit KW - antagonists & inhibitors KW - Pyridines KW - Sunitinib KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1038/s41416-019-0389-6 ER -