Wang, Ruiwei

Neuroprotective potential of ketamine prevents developing brain structure impairment and alteration of neurocognitive function induced via isoflurane through the PI3K/AKT/GSK-3β pathway. [electronic resource] - Drug design, development and therapy 2019 - 501-512 p. digital

Publication Type: Journal Article

1177-8881

10.2147/DDDT.S188636 doi


Animals
Brain--drug effects
Dose-Response Relationship, Drug
Female
Glycogen Synthase Kinase 3 beta--metabolism
Isoflurane--pharmacology
Ketamine--pharmacology
Male
Neurocognitive Disorders--chemically induced
Neuroprotective Agents--pharmacology
Phosphatidylinositol 3-Kinases--metabolism
Proto-Oncogene Proteins c-akt--metabolism
Rats
Rats, Sprague-Dawley
Signal Transduction--drug effects