TY - GEN AU - Sen,Triparna AU - Rodriguez,B Leticia AU - Chen,Limo AU - Corte,Carminia M Della AU - Morikawa,Naoto AU - Fujimoto,Junya AU - Cristea,Sandra AU - Nguyen,Thuyen AU - Diao,Lixia AU - Li,Lerong AU - Fan,Youhong AU - Yang,Yongbin AU - Wang,Jing AU - Glisson,Bonnie S AU - Wistuba,Ignacio I AU - Sage,Julien AU - Heymach,John V AU - Gibbons,Don L AU - Byers,Lauren A TI - Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer SN - 2159-8290 PY - 2020///0601 KW - Animals KW - Apoptosis KW - drug effects KW - B7-H1 Antigen KW - antagonists & inhibitors KW - CD8-Positive T-Lymphocytes KW - Cell Proliferation KW - DNA Damage KW - Female KW - Humans KW - Interferon Regulatory Factor-3 KW - genetics KW - Lung Neoplasms KW - drug therapy KW - Lymphocyte Activation KW - Membrane Proteins KW - Mice KW - Mice, Nude KW - Phthalazines KW - pharmacology KW - Piperazines KW - Poly(ADP-ribose) Polymerase Inhibitors KW - Protein Kinase Inhibitors KW - Protein Serine-Threonine Kinases KW - Pyrazines KW - Pyrazoles KW - Random Allocation KW - Small Cell Lung Carcinoma KW - T-Lymphocytes, Cytotoxic KW - Tumor Cells, Cultured KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/2159-8290.CD-18-1020 ER -