TY - GEN AU - Liu,Yang AU - Lu,Yanxin AU - Celiku,Orieta AU - Li,Aiguo AU - Wu,Qixin AU - Zhou,Yiqiang AU - Yang,Chunzhang TI - Targeting IDH1-Mutated Malignancies with NRF2 Blockade SN - 1460-2105 PY - 2020///0615 KW - Animals KW - Antineoplastic Agents KW - pharmacology KW - Antioxidants KW - Cell Line, Tumor KW - Disease Models, Animal KW - Genes, Reporter KW - Genetic Predisposition to Disease KW - Humans KW - Isocitrate Dehydrogenase KW - genetics KW - Mice KW - Models, Biological KW - Molecular Targeted Therapy KW - Mutation KW - NF-E2-Related Factor 2 KW - antagonists & inhibitors KW - Neoplasms KW - drug therapy KW - Oxidation-Reduction KW - Reactive Oxygen Species KW - metabolism KW - Signal Transduction KW - drug effects KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, N.I.H., Intramural UR - https://doi.org/10.1093/jnci/djy230 ER -