TY  - GEN
AU  - Nguyen,Quang T
AU  - Nsaibia,Mohamed J
AU  - Sirois,Martin G
AU  - Calderone,Angelino
AU  - Tardif,Jean-Claude
AU  - Fen Shi,Yan
AU  - Ruiz,Matthieu
AU  - Daneault,Caroline
AU  - Gagnon,Lyne
AU  - Grouix,Brigitte
AU  - Laurin,Pierre
AU  - Dupuis,Jocelyn
TI  - PBI-4050 reduces pulmonary hypertension, lung fibrosis, and right ventricular dysfunction in heart failure
SN  - 1755-3245
PY  - 2020///0825
KW  - Acetates
KW  - pharmacology
KW  - Animals
KW  - Cells, Cultured
KW  - Disease Models, Animal
KW  - Endothelin-1
KW  - metabolism
KW  - Extracellular Signal-Regulated MAP Kinases
KW  - Fibroblasts
KW  - drug effects
KW  - Fibrosis
KW  - Heart Failure
KW  - complications
KW  - Heart Ventricles
KW  - Humans
KW  - Hypertension, Pulmonary
KW  - etiology
KW  - Hypertrophy, Right Ventricular
KW  - Interleukin-6
KW  - Lung
KW  - Male
KW  - Phosphorylation
KW  - Pulmonary Fibrosis
KW  - Rats, Wistar
KW  - Receptors, G-Protein-Coupled
KW  - Signal Transduction
KW  - Transforming Growth Factor beta
KW  - Ventricular Dysfunction, Right
KW  - Ventricular Function, Right
KW  - Ventricular Remodeling
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1093/cvr/cvz034
ER  -