Nguyen, Quang T <br/><br/>
PBI-4050 reduces pulmonary hypertension, lung fibrosis, and right ventricular dysfunction in heart failure.  [electronic resource] 

 -  Cardiovascular research  01 2020 
 - 171-182 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1755-3245 
<br/><br/><label>Standard No.: </label>10.1093/cvr/cvz034  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acetates--pharmacology<br/>Animals<br/>Cells, Cultured<br/>Disease Models, Animal<br/>Endothelin-1--metabolism<br/>Extracellular Signal-Regulated MAP Kinases--metabolism<br/>Fibroblasts--drug effects<br/>Fibrosis<br/>Heart Failure--complications<br/>Heart Ventricles--drug effects<br/>Humans<br/>Hypertension, Pulmonary--etiology<br/>Hypertrophy, Right Ventricular--etiology<br/>Interleukin-6--metabolism<br/>Lung--drug effects<br/>Male<br/>Phosphorylation<br/>Pulmonary Fibrosis--etiology<br/>Rats, Wistar<br/>Receptors, G-Protein-Coupled--metabolism<br/>Signal Transduction<br/>Transforming Growth Factor beta--metabolism<br/>Ventricular Dysfunction, Right--etiology<br/>Ventricular Function, Right--drug effects<br/>Ventricular Remodeling--drug effects