TY - GEN AU - Ammoun,Sylwia AU - Evans,D Gareth AU - Hilton,David A AU - Streeter,Adam AU - Hayward,Christopher AU - Hanemann,C Oliver TI - Phase 0 trial investigating the intratumoural concentration and activity of sorafenib in neurofibromatosis type 2 SN - 1468-330X PY - 2020///0618 KW - Adult KW - Antineoplastic Agents KW - metabolism KW - Blotting, Western KW - Caspase 3 KW - drug effects KW - Cyclin D1 KW - Humans KW - Immunohistochemistry KW - Leukocytes, Mononuclear KW - Mitogen-Activated Protein Kinase 1 KW - Mitogen-Activated Protein Kinase 3 KW - Molecular Targeted Therapy KW - Neurofibromatosis 2 KW - drug therapy KW - Proto-Oncogene Proteins c-akt KW - Receptor, Platelet-Derived Growth Factor beta KW - Ribosomal Protein S6 KW - Sorafenib N1 - Publication Type: Letter; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1136/jnnp-2018-319713 ER -