TY - GEN AU - Tuo,Lin AU - Xiang,Jin AU - Pan,Xuanming AU - Hu,Jieli AU - Tang,Hua AU - Liang,Li AU - Xia,Jie AU - Hu,Yuan AU - Zhang,Wenlu AU - Huang,Ailong AU - Wang,Kai AU - Tang,Ni TI - PCK1 negatively regulates cell cycle progression and hepatoma cell proliferation via the AMPK/p27 SN - 1756-9966 PY - 2019///0603 KW - AMP-Activated Protein Kinases KW - genetics KW - Animals KW - Calcium-Binding Proteins KW - metabolism KW - Carcinoma, Hepatocellular KW - drug therapy KW - Cell Line, Tumor KW - Cell Proliferation KW - drug effects KW - Cyclin-Dependent Kinases KW - Down-Regulation KW - E2F Transcription Factors KW - G1 Phase Cell Cycle Checkpoints KW - Gene Knockdown Techniques KW - Glucose KW - Humans KW - Hypoglycemic Agents KW - pharmacology KW - Intracellular Signaling Peptides and Proteins KW - Liver Neoplasms KW - Male KW - Metformin KW - Mice KW - Phosphoenolpyruvate Carboxykinase (GTP) KW - Up-Regulation KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article UR - https://doi.org/10.1186/s13046-019-1029-y ER -