Tuo, Lin
PCK1 negatively regulates cell cycle progression and hepatoma cell proliferation via the AMPK/p27 [electronic resource]
- Journal of experimental & clinical cancer research : CR Feb 2019
- 50 p. digital
Publication Type: Journal Article
ISSN: 1756-9966
Standard No.: 10.1186/s13046-019-1029-y doi
Subjects--Topical Terms: AMP-Activated Protein Kinases--genetics Animals Calcium-Binding Proteins--metabolism Carcinoma, Hepatocellular--drug therapy Cell Line, Tumor Cell Proliferation--drug effects Cyclin-Dependent Kinases--metabolism Down-Regulation E2F Transcription Factors--metabolism G1 Phase Cell Cycle Checkpoints--drug effects Gene Knockdown Techniques Glucose--metabolism Humans Hypoglycemic Agents--pharmacology Intracellular Signaling Peptides and Proteins--genetics Liver Neoplasms--drug therapy Male Metformin--pharmacology Mice Phosphoenolpyruvate Carboxykinase (GTP)--genetics Up-Regulation Xenograft Model Antitumor Assays