Gemta, Lelisa F
Impaired enolase 1 glycolytic activity restrains effector functions of tumor-infiltrating CD8 [electronic resource]
- Science immunology 01 2019
Publication Type: Journal Article; Research Support, N.I.H., Extramural
2470-9468
10.1126/sciimmunol.aap9520 doi
Animals
Antineoplastic Agents, Immunological--therapeutic use
CD8-Positive T-Lymphocytes--immunology
Cell Line, Tumor
Glucose--metabolism
Glucose Transporter Type 1--metabolism
Glycolysis
Hepatitis A Virus Cellular Receptor 2--antagonists & inhibitors
Humans
Immunoglobulin G--therapeutic use
Immunotherapy, Adoptive
Lymphocytes, Tumor-Infiltrating--immunology
Melanoma--genetics
Mice, Inbred C57BL
Phosphopyruvate Hydratase--genetics
Programmed Cell Death 1 Receptor--antagonists & inhibitors