Ali, Ghada M E

Design, synthesis and biological evaluation of certain CDK2 inhibitors based on pyrazole and pyrazolo[1,5-a] pyrimidine scaffold with apoptotic activity. [electronic resource] - Bioorganic chemistry 05 2019 - 1-14 p. digital

Publication Type: Journal Article

1090-2120

10.1016/j.bioorg.2019.01.008 doi


Antineoplastic Agents--chemical synthesis
Apoptosis--drug effects
Cell Cycle--drug effects
Cell Line, Tumor
Cell Proliferation--drug effects
Cyclin-Dependent Kinase 2--antagonists & inhibitors
Dose-Response Relationship, Drug
Drug Design
Drug Screening Assays, Antitumor
Humans
Molecular Structure
Protein Kinase Inhibitors--chemical synthesis
Pyrazoles--chemical synthesis
Pyrimidines--chemical synthesis
Structure-Activity Relationship