TY - GEN AU - Adiwidjaja,Jeffry AU - Boddy,Alan V AU - McLachlan,Andrew J TI - Physiologically Based Pharmacokinetic Modelling of Hyperforin to Predict Drug Interactions with St John's Wort SN - 1179-1926 PY - 2020///0824 KW - Adult KW - Alprazolam KW - pharmacokinetics KW - Antineoplastic Agents KW - Computer Simulation KW - Cytochrome P-450 CYP2C19 KW - metabolism KW - Cytochrome P-450 CYP2C9 KW - Cytochrome P-450 CYP3A KW - Female KW - Herb-Drug Interactions KW - Humans KW - Hypericum KW - Imatinib Mesylate KW - Intestinal Mucosa KW - Liver KW - Male KW - Midazolam KW - Middle Aged KW - Models, Biological KW - Phloroglucinol KW - analogs & derivatives KW - Terpenes N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1007/s40262-019-00736-6 ER -