TY - GEN AU - Tanga,Naomi AU - Kuboyama,Kazuya AU - Kishimoto,Ayako AU - Kiyonari,Hiroshi AU - Shiraishi,Aki AU - Suzuki,Ryoko AU - Watanabe,Toshio AU - Fujikawa,Akihiro AU - Noda,Masaharu TI - The PTN-PTPRZ signal activates the AFAP1L2-dependent PI3K-AKT pathway for oligodendrocyte differentiation: Targeted inactivation of PTPRZ activity in mice SN - 1098-1136 PY - 2019///0729 KW - Adaptor Proteins, Signal Transducing KW - metabolism KW - Animals KW - Carrier Proteins KW - Cell Differentiation KW - drug effects KW - Cuprizone KW - toxicity KW - Cytokines KW - Demyelinating Diseases KW - chemically induced KW - Disease Models, Animal KW - HEK293 Cells KW - Humans KW - Immunoprecipitation KW - In Situ Nick-End Labeling KW - Luminescent Proteins KW - genetics KW - Male KW - Mice KW - Mice, Inbred C57BL KW - Mice, Transgenic KW - Microfilament Proteins KW - Myelin Proteins KW - Oligodendroglia KW - physiology KW - Proto-Oncogene Proteins c-akt KW - RNA, Small Interfering KW - Receptor-Like Protein Tyrosine Phosphatases, Class 5 KW - Signal Detection, Psychological KW - Signal Transduction KW - Transfection KW - X-Ray Microtomography KW - Red Fluorescent Protein N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1002/glia.23583 ER -