TY - GEN AU - Zhao,Min AU - Mantel,Irmela AU - Gelize,Emmanuelle AU - Li,Xinxin AU - Xie,Xiaoyue AU - Arboleda,Alejandro AU - Seminel,Marie AU - Levy-Boukris,Rinath AU - Dernigoghossian,Marilyn AU - Prunotto,Andrea AU - Andrieu-Soler,Charlotte AU - Rivolta,Carlo AU - Canonica,Jérémie AU - Naud,Marie-Christine AU - Lechner,Sebastian AU - Farman,Nicolette AU - Bravo-Osuna,Irene AU - Herrero-Vanrell,Rocio AU - Jaisser,Frederic AU - Behar-Cohen,Francine TI - Mineralocorticoid receptor antagonism limits experimental choroidal neovascularization and structural changes associated with neovascular age-related macular degeneration SN - 2041-1723 PY - 2019///0205 KW - Aged KW - Aged, 80 and over KW - Angiogenesis Inhibitors KW - therapeutic use KW - Animals KW - Choroid KW - drug effects KW - Choroidal Neovascularization KW - drug therapy KW - Drug Compounding KW - methods KW - Female KW - Gene Expression KW - Humans KW - Intravitreal Injections KW - Macular Degeneration KW - Male KW - Mice KW - Mice, Transgenic KW - Microspheres KW - Mineralocorticoid Receptor Antagonists KW - Pilot Projects KW - Prospective Studies KW - Ranibizumab KW - Rats, Long-Evans KW - Receptors, Mineralocorticoid KW - genetics KW - Receptors, Vascular Endothelial Growth Factor KW - Recombinant Fusion Proteins KW - Spironolactone KW - Treatment Outcome KW - Vascular Endothelial Growth Factor A KW - antagonists & inhibitors N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/s41467-018-08125-6 ER -