TY - GEN AU - Flint,Mike AU - Chatterjee,Payel AU - Lin,David L AU - McMullan,Laura K AU - Shrivastava-Ranjan,Punya AU - Bergeron,Éric AU - Lo,Michael K AU - Welch,Stephen R AU - Nichol,Stuart T AU - Tai,Andrew W AU - Spiropoulou,Christina F TI - A genome-wide CRISPR screen identifies N-acetylglucosamine-1-phosphate transferase as a potential antiviral target for Ebola virus SN - 2041-1723 PY - 2019///0219 KW - A549 Cells KW - Animals KW - Antiviral Agents KW - pharmacology KW - Cathepsin B KW - metabolism KW - Chlorocebus aethiops KW - Clustered Regularly Interspaced Short Palindromic Repeats KW - genetics KW - Ebolavirus KW - pathogenicity KW - Fibroblasts KW - Gene Knockout Techniques KW - Hemorrhagic Fever, Ebola KW - drug therapy KW - Humans KW - Mucolipidoses KW - Proprotein Convertases KW - antagonists & inhibitors KW - Protease Inhibitors KW - Pyrrolidines KW - Serine Endopeptidases KW - Transferases (Other Substituted Phosphate Groups) KW - Vero Cells KW - Virus Internalization KW - drug effects KW - Whole Genome Sequencing N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/s41467-018-08135-4 ER -