TY - GEN AU - Niu,Chao AU - Chen,Zhiwei AU - Kim,Kyoung Tae AU - Sun,Jia AU - Xue,Mei AU - Chen,Gen AU - Li,Santie AU - Shen,Yingjie AU - Zhu,Zhongxin AU - Wang,Xu AU - Liang,Jiaojiao AU - Jiang,Chao AU - Cong,Weitao AU - Jin,Litai AU - Li,Xiaokun TI - Metformin alleviates hyperglycemia-induced endothelial impairment by downregulating autophagy via the Hedgehog pathway SN - 1554-8635 PY - 2020///0507 KW - Animals KW - Autophagy KW - drug effects KW - Capillary Permeability KW - Cells, Cultured KW - Diabetes Mellitus, Experimental KW - complications KW - Diabetic Angiopathies KW - metabolism KW - Down-Regulation KW - Endothelium, Vascular KW - Gene Expression Regulation KW - HEK293 Cells KW - Hedgehog Proteins KW - Human Umbilical Vein Endothelial Cells KW - Humans KW - Hyperglycemia KW - Metformin KW - pharmacology KW - Mice KW - Mice, Inbred C57BL KW - Mice, Transgenic KW - Retina KW - Signal Transduction N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1080/15548627.2019.1569913 ER -