TY - GEN AU - Fiskus,Warren AU - Cai,Tianyu AU - DiNardo,Courtney D AU - Kornblau,Steven M AU - Borthakur,Gautam AU - Kadia,Tapan M AU - Pemmaraju,Naveen AU - Bose,Prithviraj AU - Masarova,Lucia AU - Rajapakshe,Kimal AU - Perera,Dimuthu AU - Coarfa,Cristian AU - Mill,Christopher P AU - Saenz,Dyana T AU - Saenz,David N AU - Sun,Baohua AU - Khoury,Joseph D AU - Shen,Yu AU - Konopleva,Marina AU - Bhalla,Kapil N TI - Superior efficacy of cotreatment with BET protein inhibitor and BCL2 or MCL1 inhibitor against AML blast progenitor cells SN - 2044-5385 PY - 2019///1230 KW - Animals KW - Antineoplastic Agents KW - pharmacology KW - Binding Sites KW - Biomarkers, Tumor KW - Cell Line, Tumor KW - Disease Models, Animal KW - Drug Synergism KW - Female KW - Humans KW - Indoles KW - Leukemia, Myeloid, Acute KW - drug therapy KW - Myeloid Cell Leukemia Sequence 1 Protein KW - antagonists & inhibitors KW - Neoplastic Stem Cells KW - drug effects KW - Protein Binding KW - Protein Kinase Inhibitors KW - Proteins KW - Proto-Oncogene Proteins c-bcl-2 KW - Pyridones KW - Sulfonamides KW - Xenograft Model Antitumor Assays N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/s41408-018-0165-5 ER -