TY - GEN AU - Edwards,Mark R AU - Forbes,Gordon AU - MacDonald,Neil AU - Berdunov,Vladislav AU - Mihaylova,Borislava AU - Dias,Priyanthi AU - Thomson,Ann AU - Grocott,Michael Pw AU - Mythen,Monty G AU - Gillies,Mike A AU - Sander,Michael AU - Phan,Tuong D AU - Evered,Lisbeth AU - Wijeysundera,Duminda N AU - McCluskey,Stuart A AU - Aldecoa,Cesar AU - Ripollés-Melchor,Javier AU - Hofer,Christoph K AU - Abukhudair,Hussein AU - Szczeklik,Wojciech AU - Grigoras,Ioana AU - Hajjar,Ludhmila A AU - Kahan,Brennan C AU - Pearse,Rupert M TI - Optimisation of Perioperative Cardiovascular Management to Improve Surgical Outcome II (OPTIMISE II) trial: study protocol for a multicentre international trial of cardiac output-guided fluid therapy with low-dose inotrope infusion compared with usual care in patients undergoing major elective gastrointestinal surgery SN - 2044-6055 PY - 2020///0210 KW - Aged KW - Cardiotonic Agents KW - administration & dosage KW - Digestive System Surgical Procedures KW - methods KW - Female KW - Fluid Therapy KW - Humans KW - Infusions, Intravenous KW - Male KW - Multicenter Studies as Topic KW - Postoperative Complications KW - prevention & control KW - Randomized Controlled Trials as Topic N1 - Publication Type: Clinical Trial Protocol; Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1136/bmjopen-2018-023455 ER -