Itkonen, Matti K <br/><br/>
Clopidogrel and Gemfibrozil Strongly Inhibit the CYP2C8-Dependent Formation of 3-Hydroxydesloratadine and Increase Desloratadine Exposure In Humans.  [electronic resource] 

 -  Drug metabolism and disposition: the biological fate of chemicals  04 2019 
 - 377-385 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1521-009X 
<br/><br/><label>Standard No.: </label>10.1124/dmd.118.084665  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adult<br/>Area Under Curve<br/>Aryl Hydrocarbon Hydroxylases--metabolism<br/>Biotransformation--physiology<br/>Clopidogrel--pharmacology<br/>Cross-Over Studies<br/>Cytochrome P-450 CYP2C8--metabolism<br/>Cytochrome P-450 CYP2C8 Inhibitors--poisoning<br/>Drug Interactions--physiology<br/>Female<br/>Gemfibrozil--pharmacology<br/>Genotype<br/>Glucuronides--pharmacology<br/>Humans<br/>Hypolipidemic Agents--poisoning<br/>Loratadine--analogs & derivatives<br/>Male<br/>Young Adult