TY - GEN AU - He,Lian-Jun AU - Zhu,Yi-Bao AU - Fan,Qing-Zhu AU - Miao,Dong-Dong AU - Zhang,Sheng-Peng AU - Liu,Xiao-Ping AU - Zhang,Chao TI - Shape-based virtual screen for the discovery of novel CDK8 inhibitor chemotypes SN - 1464-3405 PY - 2020///0305 KW - Cell Proliferation KW - drug effects KW - Colorectal Neoplasms KW - pathology KW - Cyclin-Dependent Kinase 8 KW - antagonists & inhibitors KW - Drug Discovery KW - Drug Screening Assays, Antitumor KW - G1 Phase KW - HCT116 Cells KW - Humans KW - Molecular Docking Simulation KW - Phosphorylation KW - Protein Kinase Inhibitors KW - chemistry KW - S Phase KW - STAT1 Transcription Factor KW - metabolism N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.bmcl.2018.12.065 ER -