He, Lian-Jun <br/><br/>
Shape-based virtual screen for the discovery of novel CDK8 inhibitor chemotypes.  [electronic resource] 

 -  Bioorganic & medicinal chemistry letters  02 2019 
 - 549-555 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1464-3405 
<br/><br/><label>Standard No.: </label>10.1016/j.bmcl.2018.12.065  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Cell Proliferation--drug effects<br/>Colorectal Neoplasms--pathology<br/>Cyclin-Dependent Kinase 8--antagonists & inhibitors<br/>Drug Discovery<br/>Drug Screening Assays, Antitumor<br/>G1 Phase--drug effects<br/>HCT116 Cells<br/>Humans<br/>Molecular Docking Simulation<br/>Phosphorylation<br/>Protein Kinase Inhibitors--chemistry<br/>S Phase--drug effects<br/>STAT1 Transcription Factor--metabolism