TY - GEN AU - Kleinjan,Jan P AU - Brinkman,Ithamar AU - Bakema,Robbert AU - van Zanden,Jelmer J AU - van Rooijen,Johan M TI - Tolerance-based capecitabine dose escalation after DPYD genotype-guided dosing in heterozygote DPYD variant carriers: a single-center observational study SN - 1473-5741 PY - 2020///0909 KW - Adult KW - Aged KW - Aged, 80 and over KW - Antimetabolites, Antineoplastic KW - administration & dosage KW - Capecitabine KW - Dihydrouracil Dehydrogenase (NADP) KW - genetics KW - Female KW - Follow-Up Studies KW - Genotype KW - Heterozygote KW - Humans KW - Male KW - Middle Aged KW - Neoplasms KW - drug therapy KW - Polymorphism, Single Nucleotide KW - Practice Guidelines as Topic KW - standards KW - Prognosis KW - Retrospective Studies KW - Survival Rate N1 - Publication Type: Clinical Trial; Journal Article; Observational Study UR - https://doi.org/10.1097/CAD.0000000000000748 ER -