TY  - GEN
AU  - Boyaci,Hande
AU  - Chen,James
AU  - Jansen,Rolf
AU  - Darst,Seth A
AU  - Campbell,Elizabeth A
TI  - Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding
SN  - 1476-4687
PY  - 2019///0715
KW  - Bacterial Proteins
KW  - metabolism
KW  - Base Sequence
KW  - Catalytic Domain
KW  - Cryoelectron Microscopy
KW  - DNA, Bacterial
KW  - chemistry
KW  - DNA-Directed RNA Polymerases
KW  - Enzyme Stability
KW  - drug effects
KW  - Escherichia coli
KW  - enzymology
KW  - Lactones
KW  - pharmacology
KW  - Models, Molecular
KW  - Mycobacterium tuberculosis
KW  - Nucleic Acid Conformation
KW  - Nucleic Acid Denaturation
KW  - Promoter Regions, Genetic
KW  - Protein Binding
KW  - Thermodynamics
KW  - Transcription Initiation, Genetic
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/s41586-018-0840-5
ER  -