TY - GEN AU - Gavilá,Joaquín AU - Oliveira,Mafalda AU - Pascual,Tomás AU - Perez-Garcia,Jose AU - Gonzàlez,Xavier AU - Canes,Jordi AU - Paré,Laia AU - Calvo,Isabel AU - Ciruelos,Eva AU - Muñoz,Montserrat AU - Virizuela,Juan A AU - Ruiz,Isabel AU - Andrés,Raquel AU - Perelló,Antonia AU - Martínez,Jerónimo AU - Morales,Serafín AU - Marín-Aguilera,Mercedes AU - Martínez,Débora AU - Quero,Juan C AU - Llombart-Cussac,Antonio AU - Prat,Aleix TI - Safety, activity, and molecular heterogeneity following neoadjuvant non-pegylated liposomal doxorubicin, paclitaxel, trastuzumab, and pertuzumab in HER2-positive breast cancer (Opti-HER HEART): an open-label, single-group, multicenter, phase 2 trial SN - 1741-7015 PY - 2019///0705 KW - Adult KW - Aged KW - Antibodies, Monoclonal, Humanized KW - administration & dosage KW - Antineoplastic Combined Chemotherapy Protocols KW - therapeutic use KW - Breast Neoplasms KW - drug therapy KW - Cardiotoxicity KW - epidemiology KW - Chemotherapy, Adjuvant KW - adverse effects KW - Doxorubicin KW - Female KW - Humans KW - Middle Aged KW - Neoadjuvant Therapy KW - Paclitaxel KW - Polyethylene Glycols KW - Receptor, ErbB-2 KW - Trastuzumab N1 - Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1186/s12916-018-1233-1 ER -